原创《糖尿病周围神经病肌力和复合肌肉动作电位波幅的相关性》：这是一篇与动作电位论文范文相关的免费优秀学术论文范文资料,为你的论文写作提供参考。
【摘 要】 目的 探讨糖尿病周围神经病（DPN）患者双下肢肌力与腓总神经运动传导的复合肌肉动作电位（CMAP）波幅的相关性.方法 75例DPN患者, 根据患者下肢肌力分为轻度无力组（3级和4级, 32例）和肌力正常组（5级, 43例）.采用肌电/诱发电位仪记录腓总神经运动传导速度（MCV）、远端潜伏期（DPL）及复合肌肉动作电位（CMAP）的波幅、时限、波形, 对数据进行分析.结果 轻度无力组MCV减慢10例（31.3%）；DPL延长5例（15.6%）；肌力正常组MCV减慢13例（30.2%）；DPL延长6例（14.0%）；两组MCV、DPL参数比较差异无统计学意义（P>0.05）.轻度无力組CMAP平均波幅为（3.3±0.3）mV,
肌力正常组为（5.1±0.2）mV, 比较差异有统计学意义（P<0.05）.两组平均时限比较差异无统计学意义（P>0.05）.轻度无力组CMAP波幅下降率（40.6%）高于肌力正常组（16.3%）, 差异有统计学意义（P<0.05）；两组时限异常率、CMAP波形变异率比较差异无统计学意义（P>0.05）.结论 CMAP的波幅与DPN患者肌力相关, 可以反映其运动神经轴索损害, 结合观察CMAP波形变异有助于提高DPN的检出率.
【关键词】 复合肌肉动作电位；腓总神经；糖尿病周围神经病
DOI：10.14163/j.cnki.11-5547/r.2017.19.005
Correlation study between muscle strength and CMAP amplitude in diabetic peripheral neuropathy LI Bo, TAN Xue-mei. Department of Neurology, Beijing City Hepingli Hospital, Beijing 100013, China
【Abstract】 Objective To explore the correlation between both lower extremities and common peroneal nerve motor conducted compound muscle action potential （CMAP）amplitude. Methods A total of 75 DPN patients were divided by lower limb muscle strength into mild weakness group （grade 3 and 4, 32 cases）and normal muscle strength group （grade 5, 43 cases）. Motor conduction velocity （MCV）of common peroneal nerve, distal latency （DPL）and amplitude, time limit, weform of composite muscle action potential （CMAP）were recorded by electromyography / evoked potentials. The data were analyzed. Results Mild weakness group had MCV slowing down in 10 cases （31.3%） and DPL extension in 5 cases （15.6%）, while normal muscle strength group had MCV slowing down in 13 cases （30.2%） and DPL extension in 6 cases （14.0%）. Both groups had no statistically significant difference in MCV and DPL parameters （P>0.05）. Mild weakness group had erage CMAP amplitude as （3.3±0.3） mV, which was （5.1±0.2） mV in normal muscle strength group, and the difference had statistical significance （P<0.05）. Both groups had no statistically significant difference in average time limit （P>0.05）. Mild weakness group had had higher CMAP amplitude decline rate （40.6%） than normal muscle strength group （16.3%）, and the difference had statistical significance （P<0.05）. Both groups had no statistically significant difference in abnormal time limit rate and CMAP waveform variation rate （P>0.05）. Conclusion The amplitude of CMAP is related to the muscle strength of DPN patients, which can reflect the damage of motor axon. It is helpful to improve the detection rate of DPN by observing CMAP weform variation.
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