分类筛选
分类筛选:

关于胸腔积液论文范文资料 与香菇多糖联合化疗药物治疗恶性胸腔积液的临床效果有关论文参考文献

版权:原创标记原创 主题:胸腔积液范文 科目:职称论文 2024-02-27

《香菇多糖联合化疗药物治疗恶性胸腔积液的临床效果》:此文是一篇胸腔积液论文范文,为你的毕业论文写作提供有价值的参考。

【摘 要】 目的 评价香菇多糖联合化疗药物治疗恶性胸腔积液(MPE)的临床效果.方法 62例恶性胸腔积液患者, 均使用中心静脉导管引流, 使胸水流尽后, 按随机原则分为对照组(30例)与治疗组(32例).对照组在胸腔内注入顺铂, 治疗组在此基础上加用香菇多糖胸腔内注入.比较两组的治疗效果.结果 经治疗, 治疗组临床症状有效率为68.75%, 优于对照组的40.00%, 差异具有统计学意义(P<0.05).治疗组生活质量有效率为87.50%, 优于对照组的56.67%, 差异具有统计学意义(P<0.01).治疗组发热、胸痛、恶心呕吐发生率分别为9.38%、6.25%、0, 均低于对照组的30.00%、26.67%、20.00%, 差异均具有统计学意义(P<0.05).结论 香菇多糖联合化疗药物胸腔注入治疗恶性胸腔积液疗效显著, 提高患者的生活质量, 减轻化疗的毒副反应.

【关键词】 香菇多糖;化疗药物;恶性胸腔积液;临床效果

DOI:10.14163/j.cnki.11-5547/r.2017.18.054

【Abstract】 Objective To evaluate the clinical effect of letinous edodes polysaccharide combined with chemotherapeutics in the treatment of malignant pleural effusion (MPE). Methods A total of 62 malignant pleural effusion patients all received central venous tube drainage, and they were randomly divided into control group (30 cases) and treatment group (32 cases) after hing been drained away the pleural effusion. The control group received injection of cis-platinum to thoracic city, and the treatment group also received injection of letinous edodes polysaccharide to thoracic city. Therapeutic effect was compared in two groups. Results After treatment, the treatment group had better clinical symptom effective rate as 68.75% than 40.00% in the control group, and the difference had statistical significance (P<0.05). The treatment group had better quality of life effective rate as 87.50% than 56.67% in the control group, and the difference had statistical significance (P<0.01). The treatment group had lower incidence of fever, chest pain and nausea and vomiting respectively as 9.38%, 6.25% and 0 than 30.00%, 26.67% and 20.00% in the control group, and their difference had statistical significance (P<0.05). Conclusion Combination of letinous edodes polysaccharide and chemotherapeutics injection of thoracic cavity shows significant curative effect in treating malignant pleural effusion; Clinical effect, and it can improve quality of life in patients and reduce adverse reactions of chemotherapy.

【Key words】 Letinous edodes polysaccharide; Chemotherapeutics; Malignant pleural effusion; Clinical effect

惡性胸腔积液(MPE)为一种临床肿瘤患者常见并发症.是由肺癌以及其他部位恶性肿瘤累及胸膜或胸膜原发性肿瘤引起的胸腔积液, 多数症状顽固, 难以缓解[1].近年来, 随着临床治疗学深入研究, 胸腔内化疗可直接杀灭癌细胞, 达到消除胸水的目的.现对本院收治的恶性肿瘤患者采用香菇多糖联合顺铂治疗方法经中心静脉导管引流至无胸水后注入胸腔, 从而减轻患者的痛苦、提高患者的生存质量并取得满意临床效果.现报告如下.

1 资料与方法

1. 1 一般资料 选取2011年9月~2016年9月本院收治的62例患者, 均采用病理学以及细胞学诊断确诊为晚期恶性肿瘤患者, 经X线诊断、B超检查诊断结果为大量或中量胸腔积液, 患者均使用中心静脉导管引流, 使胸水流尽后, 将其随机分为对照组(30例)与治疗组(32例).对照组中男20例, 女10例, 年龄26~69岁, 平均年龄(49.6±6.5)岁, 病程4 d~6个月, 平均病程(70±37)d.治疗组中男23例, 女9例, 年龄26~66岁, 平均年龄(47.0±6.3)岁, 病程10 d~5个月, 平均病程(75±25)d.两组患者一般资料比较差异无统计学意义(P>0.05), 具有可比性.

胸腔积液论文参考资料:

结论:香菇多糖联合化疗药物治疗恶性胸腔积液的临床效果为关于本文可作为胸腔积液方面的大学硕士与本科毕业论文胸腔积液论文开题报告范文和职称论文论文写作参考文献下载。

和你相关的