原创《社区卫生服务中心尿路感染病原菌分布耐药性分析》：本论文主要论述了尿路感染论文范文相关的参考文献,对您的论文写作有参考作用。
摘 要 目的：了解并分析社区医院住院患者尿路感染的病原菌分布、构成及耐药状况,为指导临床合理使用抗菌药物提供依据.方法：收集2015年1月—2016年1月住院尿路感染患者送检的中段尿标本169份,进行培养、分离、鉴定及药敏分析.结果：169份标本中分别检出革兰阴性杆菌129株（76.3%）、肠球菌属24株（14.2%）、葡萄球菌属13株（7.7%）、真菌3株（1.8%）；产超广谱-内酰胺酶（ESBLs）大肠埃希菌的检出率为39.7%.革兰阴性杆菌对头孢替坦、头孢他啶、头孢吡肟、哌拉西林/他唑巴坦、阿米卡星、亚胺培南的敏感性较好,对氨苄西林、磺胺类抗生素耐药率高；革兰阳性球菌对万古霉素、利奈唑胺敏感.结论：社区住院患者尿路感染的主要病原菌为革兰阴性杆菌,病原菌耐药性较高,真菌感染较少见.临床应结合药敏试验和耐药菌株的检测结果,合理使用抗菌药物.
关键词 尿路感染；病原菌；耐药性
中图分类号：R691.3 文献标志码：A 文章编号：1006-1533（2017）02-0022-03
Analysis of the distribution and the drug resistance of pathogenic bacteria of urinary tract infection in the community health service center
WANG Jun1, XU Min2, WANG Lingchuang1, XIE Yusu1, BAO Yao1, WANG Xiaohong1, LING Feng1（1.Longhua Community Health Service Center of Xuhui District, Shanghai 200236, China； 2. Central Hospital of Xuhui District, Shanghai
200031, China）
ABSTRACT Objective： To understand and analyze the distribution, composition and drug resistance of urinary tract infection of the in-patients in the community hospital to provide the evidence for clinical rational use of antibiotics. Methods： From January 2015 to January 2016, 169 urine specimens from patients with urinary tract infection submitted for censorship were collected for culture, isolation, identification and drug sensitivity analysis. Results： In 169 samples, 129 strains of gram negative bacilli（76.3%）, 24 strains of enterococcus（14.2%）, 13 strains of staphylococcus（7.7%）, and 3 strains of fungi（1.8%） were detected. The detection rate of extended spectrum β lactamases（ESBLs）producing escherichia coli was 39.7%. Gram negative bacilli were sensitive to cefotetan, ceftazidime, cefepime, piperacillin/tazobactam, amikacin and imipenem, while highly resistant to ampicillin and sulfonamides. Gram positive cocci were sensitive to vancomycin and linezolid. Conclusion： The main pathogenic bacteria of urinary tract infection in the community hospital in-patients are gram-negative bacilli, the drug resistance of pathogenic bacteria is high and fungal infection is rare. Combined with clinical drug sensitivity tests and resistant strain reports, the antimicrobial should be rationally used.
KEY WORDS urinary tract infection； pathogenic bacterium； drug resistance
尿路感染是致病菌在尿路及尿液中生長繁殖,并侵犯尿路黏膜和组织而引起的感染性疾病[1].社区住院患者由于多为高龄、前列腺增生、脑血管疾病后长期卧床及留置导尿等因素,导致尿路感染尤其多发.而临床医生大多采用经验性抗生素治疗,常导致治疗不合理或不彻底,造成细菌耐药性增加,且社区医院诊疗条件有限,后续治疗也面临很大困难.了解社区住院患者尿路感染病原菌的分布及耐药性,对防控感染和合理应用抗生素有重要意义.本文通过分析我院尿路感染患者中段尿培养的病原菌分布及耐药性,为临床医生了解社区住院泌尿系感染病原微生物的耐药状况及临床用药、制定经验性治疗策略提供帮助.
尿路感染论文参考资料：
结论：社区卫生服务中心尿路感染病原菌分布耐药性分析为适合尿路感染论文写作的大学硕士及相关本科毕业论文，相关女性尿道感染能自愈吗开题报告范文和学术职称论文参考文献下载。
