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关于糖皮质激素论文范文资料 与不同停药方式糖皮质激素治疗亚急性甲状腺炎临床疗效对析有关论文参考文献

版权:原创标记原创 主题:糖皮质激素范文 科目:职称论文 2024-02-15

《不同停药方式糖皮质激素治疗亚急性甲状腺炎临床疗效对析》:本论文主要论述了糖皮质激素论文范文相关的参考文献,对您的论文写作有参考作用。

[摘 要] 目的 研究并分析治疗亚急性甲状腺炎患者时使用不同停药方式糖皮质激素的效果.方法 方便选取2015年12月—2016年12月该院收集的亚急性甲状腺炎患者共96例,通过区组随机化分为对照组(48例)和观察组(48例),均接受糖皮质激素治疗,对照组在红细胞沉降率恢复正常后停用糖皮质激素治疗,观察组在治疗2周后逐步减少剂量直到用药结束,将两组临床疗效、停药3个月后亚急性甲状腺炎的复发率和不良反应情况进行观察和对比.结果 观察组的总有效率为97.92%,显著高于对照组的77.08%(χ2等于9.524,P等于0.002),对照组停药后复发率为14.60%,远高于观察组的0.00%,两组患者对比差异有统计学意义(P<0.05).观察组不良反应率为16.70%,低于对照组的27.10%,两组患者对比差异有统计学意义(P<0.05).结论 在亚急性甲状腺炎患者的治疗过程中,尽快使用足量的糖皮质激素并逐渐缓慢减量能够显著提升临床疗效,值得推广应用.

[关键词] 亚急性;甲状腺炎;糖皮质激素;治疗效果

[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2018)02(c)-0112-03

Comparison of Clinical Efficacy of Glucocorticoid in the Treatment of Subacute Thyroiditis with Different Ways of Withdrawal

WU Jiang

First Branch of the Ninth Division of Xinjiang Production and Construction Corps, Tacheng, Xinjiang, 834601 China

[Abstract] Objective This paper tries to study and analyze the effect of different dosage forms of glucocorticoid in patients with subacute thyroiditis. Methods A total of 96 patients with subacute thyroiditis collected from December 2015 to December 2016 were convenient selected and randomly divided into control group (n 等于 48) and observation group (n 等于 48) Corticosteroid treatment, the control group in the erythrocyte sedimentation rate returned to normal after the corticosteroid treatment disabled, the observation group in the treatment after 2 weeks to gradually reduce the dose until the end of medication, the two groups of clinical efficacy, withdrawal 3 months after subacute thyroiditis The recurrence rate and adverse reactions were observed and contrast. Results The total effective rate was 97.92% in the observation group, which was significantly higher than that in the control group 77.08%(χ2等于9.524, P等于0.002). The relapse rate was 14.60% in the control group, which was much higher than that in the observation group(0.00%), There was significant difference between the two groups(P<0.05). The adverse reaction rate was 16.70% in the observation group and 27.10% in the control group, the difference was statistically significant (P<0.05). Conclusion In the treatment of subacute thyroiditis patients, the use of sufficient amount of glucocorticoid as soon as possible and gradually slow down the reduction can significantly improve the clinical efficacy, it is worth promoting the application.

[Key words] Subacute; Thyroiditis; Glucocorticoid; Treatment effect

亞急性甲状腺炎临床上也称为亚急性肉芽肿性甲状腺炎或病毒性甲状腺炎,亚急性甲状腺炎通常由病毒感染引发,临床表现包括了发热、甲状腺肿痛、甲状腺毒症.研究发现针对患者病情程度的差异,应给予不同的治疗方式,尤其是病情较为严重的患者应通过糖皮质激素口服进行治疗[1].在我国近年来亚急性甲状腺炎临床上呈现逐渐增多现象,而且患者临床情况变化比较复杂,在一些医院中存在误诊或漏诊的可能性,且容易反复发作,导致患者健康水平下降,增加患者心理负担.在该次研究中方便选取了该院自2015年12月—2016年12月间收集的亚急性甲状腺炎患者共96例,对其采用了糖皮质激素不同停药方式干预,现报道如下.

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结论:不同停药方式糖皮质激素治疗亚急性甲状腺炎临床疗效对析为适合不知如何写糖皮质激素方面的相关专业大学硕士和本科毕业论文以及关于糖皮质激素软膏论文开题报告范文和相关职称论文写作参考文献资料下载。

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